STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Tlie_1237PFAM: Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: aco:Amico_1360 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase family protein. (246 aa)    
Predicted Functional Partners:
Tlie_1235
PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; histidinol-phosphate phosphatase family domain; histidinol-phosphatase; COGs: COG0241 Histidinol phosphatase and related phosphatase; InterPro IPR004446: IPR006543: IPR006549; KEGG: aco:Amico_1357 histidinol-phosphate phosphatase family protein; PRIAM: Histidinol-phosphatase; SPTR: D,D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; D,D-heptose 1,7-bisphosphate phosphatase; hydrolase, HAD-superfamily, su [...]
 0.997
Tlie_1138
PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor SelB, winged helix; TIGRFAM: selenocysteine-specific elongation factor SelB; small GTP-binding protein domain; translation elongation factor TU; COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR018247: IPR000795: IPR005225: IPR004535: IPR 004161: IPR015191; KEGG: aco:Amico_1156 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; SPTR: Sel [...]
   
 0.954
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
  
 0.939
Tlie_1236
PFAM: NAD dependent epimerase/dehydratase family; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: aco:Amico_1359 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative GDP-D-mannose dehydratase.
 
 
 0.928
Tlie_1572
Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR005844: IPR005845: IPR005846: IPR005843: IPR 005841: IPR016066; KEGG: aco:Amico_0419 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/p [...]
 
  
 0.866
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
  
 0.806
Tlie_1239
PFAM: Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: tai:Taci_0801 two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family.
       0.757
Tlie_1359
PFAM: Heavy-metal-associated domain; InterPro IPR017969: IPR006121; KEGG: aco:Amico_1897 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Heavy metal transport/detoxification protein.
   
   0.623
Tlie_1234
PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein; InterPro IPR005242; KEGG: aco:Amico_1356 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.619
Tlie_1232
methylated-DNA/protein- cysteinemethyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR001497: IPR014048; KEGG: psl:Psta_3745 methylated-DNA/protein-cysteinemethyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: Methylated-DNA-[protein]-cysteine S-methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase.
     
 0.610
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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