STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1276Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018: IPR006674: IPR003607; KEGG: tai:Taci_0059 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase. (714 aa)    
Predicted Functional Partners:
Tlie_1854
PFAM: GGDEF domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR000014: IPR000160: IPR013767; KEGG: tit:Thit_0615 response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; SPTR: Response regulator r [...]
 
 0.968
Tlie_1594
Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000014: IPR000160: IPR000700: IPR013656; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein.
 
 0.958
Tlie_0055
Diguanylate cyclase with PAS/PAC and GAF sensors; PFAM: GAF domain; GGDEF domain; PAS fold; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterProIPR003018: IPR000160: IPR000014: IPR013656: IPR 000700; KEGG: aco:Amico_1621 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein.
 
 0.924
Tlie_1684
Putative PAS/PAC sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2206 HD-GYP domain; InterProIPR000014: IPR000700: IPR013655: IPR006674: IPR 001610; KEGG: dak:DaAHT2_2363 putative PAS/PAC sensor protein; PFAM: PAS fold-3 domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: PAC repeat-containing protein; PAS domain containing protein; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein.
 
 
 0.903
Tlie_0181
Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein.
 
 0.872
Tlie_1753
PFAM: GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018; KEGG: aco:Amico_1621 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase.
  
 0.863
Tlie_0064
Putative PAS/PAC sensor protein; PFAM: HD domain; PAS fold; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: PAS domain S-box; uncharacterized domain HDIG; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR001638: IPR000014: IPR003607: IPR006675: IPR 013656: IPR006674; KEGG: tle:Tlet_1338 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; extracellular solute-binding protein family 3; PAS fold-4 domain protein; SMART: extracellular solute-binding protein family 3; PAS domain c [...]
 
 
0.854
Tlie_0254
PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR003018: IPR000160; KEGG: tai:Taci_1538 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase.
  
 0.812
Tlie_0357
Diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: mgm:Mmc1_3430 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase.
 
  
 0.785
Tlie_0036
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: aco:Amico_1683 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family.
 
 
 0.781
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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