STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1407PFAM: Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR018211: IPR001670; KEGG: pth:PTH_0851 alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Alcohol dehydrogenase. (388 aa)    
Predicted Functional Partners:
Tlie_0209
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR012408; KEGG: tjr:TherJR_0630 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: CoA-dependent propionaldehyde dehydrogenase.
 
 0.945
Tlie_1406
CoA-binding domain protein; PFAM: CoA binding domain; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781: IPR013650: IPR011761; KEGG: tai:Taci_1407 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-grasp domain protein; SPTR: Acetyl-CoA synthetase / acetyltransferase family protein.
     
 0.671
plsY
Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
  
    0.664
Tlie_1408
ErfK/YbiS/YcfS/YnhG family protein; PFAM: L,D-transpeptidase catalytic domain; COGs: COG1376 conserved hypothetical protein; InterPro IPR005490; KEGG: aco:Amico_0482 ErfK/YbiS/YcfS/YnhG family protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; SPTR: ErfK/YbiS/YcfS/YnhG family protein.
       0.664
Tlie_1402
PFAM: ATP:guanido phosphotransferase, C-terminal catalytic domain; COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: tai:Taci_1403 ATP:guanido phosphotransferase; PFAM: ATP:guanido phosphotransferase; SPTR: ATP:guanido phosphotransferase domain protein.
  
   0.509
Tlie_1404
Transcriptional repressor, CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR); COGs: COG4463 Transcriptional repressor of class III stress genes; InterPro IPR008463; KEGG: aco:Amico_0562 transcriptional repressor, CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; SPTR: Transcriptional repressor, CtsR.
     
 0.490
Tlie_1403
PFAM: UvrB/uvrC motif; COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: bmd:BMD_0103 modulator of CtsR repression, McsA; PFAM: UvrB/UvrC protein; SPTR: UvrB/uvrC motif protein.
       0.479
Tlie_1409
Hypothetical protein; KEGG: ske:Sked_17430 CDP-diacylglycerol inositol 3-phosphatidyltransferase; SPTR: CDP-diacylglycerol inositol 3-phosphatidyltransferase.
       0.466
Tlie_1401
ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR001270: IPR018368: IPR004176: IPR003959: IPR 001943: IPR013093: IPR019489: IPR003593; KEGG: tai:Taci_1402 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: Negative [...]
  
  
 0.454
Tlie_0505
Protein of unknown function DUF2229, CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR011461: IPR002731: IPR018709; KEGG: pmo:Pmob_1610 CoA-substrate-specific enzyme activase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase BadF/BadG/BcrA/BcrD type; protein of unknown function DUF1567; SPTR: Putative CoA-substrate-specific enzyme activase.
   
  
 0.426
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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