STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1435PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: dau:Daud_1549 iron dependent repressor; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Manganese-dependent transcription regulator. (159 aa)    
Predicted Functional Partners:
Tlie_1203
PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: aco:Amico_1266 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH ubiquinone oxidoreductase 20 kDa subunit.
    
   0.802
Tlie_1534
PFAM: Ferric uptake regulator family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: aco:Amico_0020 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: Transcriptional regulator, Fur family; Belongs to the Fur family.
  
  
 0.657
Tlie_1437
Helix-turn-helix domain protein; PFAM: Helix-turn-helix; InterPro IPR001387; KEGG: aco:Amico_0543 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family.
  
  
 0.609
Tlie_1436
Triphosphoribosyl-dephospho-CoA synthase; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736; KEGG: tai:Taci_0595 triphosphoribosyl-dephospho-CoA synthase; PFAM: triphosphoribosyl-dephospho-CoA protein; PRIAM: Triphosphoribosyl-dephospho-CoA synthase; SPTR: Triphosphoribosyl-dephospho-CoA synthase.
       0.552
Tlie_1434
PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein; COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: aco:Amico_0545 YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: Putative YbaK/ebsC protein.
       0.546
Tlie_0152
ABC-3 protein; PFAM: ABC 3 transport family; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: mar:MAE_52810 ABC-3 transport family protein; PFAM: ABC-3 protein; SPTR: Similar to A1IAV0_9DELT Putative Mn/Zn ABC transporter.
  
  
 0.509
Tlie_1438
PFAM: Radical SAM superfamily; COGs: COG1243 Histone acetyltransferase; InterPro IPR007197: IPR006638; KEGG: aco:Amico_0542 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
       0.481
tpx
Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.473
Tlie_0153
PFAM: ABC transporter; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593: IPR003439; KEGG: syp:SYNPCC7002_A2500 ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter.
  
  
 0.462
Tlie_0472
Zinc/iron permease; PFAM: ZIP Zinc transporter; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cbf:CLI_1259 ZIP family zinc transporter; PFAM: zinc/iron permease; SPTR: Zinc transporter, ZIP family.
  
  
 0.448
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.