STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1439PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: swo:Swol_1820 Na+-driven multidrug efflux pump-like protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein. (451 aa)    
Predicted Functional Partners:
Tlie_0995
Glyceraldehyde-3-phosphate dehydrogenase (NAD+); PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020830: IPR020831: IPR020832: IPR006424: IPR 020828: IPR020829; KEGG: aco:Amico_0834 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, cata [...]
   
  
 0.734
Tlie_0878
SSU ribosomal protein S1P; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: aco:Amico_1023 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: RNA binding S1 domain protein.
  
    0.710
Tlie_1438
PFAM: Radical SAM superfamily; COGs: COG1243 Histone acetyltransferase; InterPro IPR007197: IPR006638; KEGG: aco:Amico_0542 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
       0.639
Tlie_1437
Helix-turn-helix domain protein; PFAM: Helix-turn-helix; InterPro IPR001387; KEGG: aco:Amico_0543 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family.
  
  
 0.587
Tlie_1436
Triphosphoribosyl-dephospho-CoA synthase; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736; KEGG: tai:Taci_0595 triphosphoribosyl-dephospho-CoA synthase; PFAM: triphosphoribosyl-dephospho-CoA protein; PRIAM: Triphosphoribosyl-dephospho-CoA synthase; SPTR: Triphosphoribosyl-dephospho-CoA synthase.
       0.548
Tlie_1440
PFAM: SIS domain; Helix-turn-helix domain, rpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281: IPR001347; KEGG: tai:Taci_0584 transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family.
       0.539
Tlie_0851
Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008135: IPR001453: IPR008136; KEGG: aco:Amico_0392 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: competence/damag [...]
 
   
 0.516
Tlie_1435
PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: dau:Daud_1549 iron dependent repressor; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Manganese-dependent transcription regulator.
  
    0.419
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
Server load: low (14%) [HD]