STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1450PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: drm:Dred_0416 regulatory proteins, IclR; PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: Transcriptional regulator, IclR family. (250 aa)    
Predicted Functional Partners:
Tlie_0280
PFAM: Allophanate hydrolase subunit 1; TIGRFAM: TIGR00370 family protein; COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833: IPR010016; KEGG: aco:Amico_0496 allophanate hydrolase subunit 1; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Allophanate hydrolase, subunit 1.
  
    0.764
Tlie_0279
Urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: aco:Amico_0497 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; PRIAM: Urea carboxylase; SMART: Allophanate hydrolase subunit 2; SPTR: Urea amidolyase related protein; TIGRFAM: urea amidolyase related protein.
  
    0.740
Tlie_0277
PFAM: Protein of unknown function (DUF1445); COGs: COG4336 conserved hypothetical protein; InterPro IPR009906: IPR016938; KEGG: aco:Amico_0499 protein of unknown function DUF1445; PFAM: protein of unknown function DUF1445; SPTR: Putative uncharacterized protein; Belongs to the D-glutamate cyclase family.
  
    0.502
glnS
PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase; COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterProIPR020060: IPR001412: IPR020058: IPR020059: IPR 004514; KEGG: tai:Taci_1596 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; SPTR: Glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase.
       0.484
Tlie_0032
GntR domain protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: pth:PTH_2232 transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR domain protein.
  
  
 0.472
Tlie_1674
Putative lipoprotein; PFAM: Tripartite tricarboxylate transporter family receptor; COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: bcg:BCG9842_B4344 putative lipoprotein; SPTR: Putative uncharacterized protein.
 
  
 0.448
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.421
Tlie_0322
PFAM: Major Facilitator Superfamily; COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: aco:Amico_0348 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1.
 
  
 0.413
Tlie_1676
Protein of unknown function DUF112 transmembrane; PFAM: Tripartite tricarboxylate transporter TctA family; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: bhy:BHWA1_02095 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative uncharacterized protein.
 
    0.404
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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