STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1554AAA ATPase; PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; InterPro IPR000764: IPR003593; KEGG: tai:Taci_1361 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase. (545 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.990
Tlie_0779
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.930
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.930
cmk
PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase; COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR000623: IPR011994; KEGG: brm:Bmur_0695 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase.
   
 
 0.922
Tlie_0889
Thymidine phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase; COGs: COG0213 Thymidine phosphorylase; InterProIPR000053: IPR017872: IPR017459: IPR000312: IPR 013102: IPR018090; KEGG: aco:Amico_1012 pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like; PRIAM: Thymidine phosphorylase; SPTR: Pyrimidine-nucleoside phosphorylase; TI [...]
    
 0.919
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 0.918
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.914
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.910
Tlie_0772
MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518: IPR011551; KEGG: aco:Amico_0750 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG protein; TIGRFAM: MazG family protein.
    
  0.904
Tlie_0995
Glyceraldehyde-3-phosphate dehydrogenase (NAD+); PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020830: IPR020831: IPR020832: IPR006424: IPR 020828: IPR020829; KEGG: aco:Amico_0834 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, cata [...]
  
 
 0.890
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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