STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1561Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; InterPro IPR006675: IPR006674; KEGG: tai:Taci_1363 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase. (181 aa)    
Predicted Functional Partners:
Tlie_1562
PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR011826: IPR006251: IPR001030; KEGG: tai:Taci_1364 homoaconitate hydratase family protein; PFAM: aconitate hydratase domain-containing protein; SPTR: Homoaconitate hydratase family protein; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase.
 
     0.820
Tlie_1566
PFAM: Isocitrate/isopropylmalate dehydrogenase; COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804: IPR019818; KEGG: tai:Taci_1368 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase.
 
     0.772
leuC-2
Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
     0.754
leuD-2
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
     0.746
leuD-3
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
     0.735
Tlie_0491
PFAM: Saccharopine dehydrogenase; COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: kko:Kkor_1137 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: Saccharopine dehydrogenase.
  
     0.708
Tlie_1560
GntR domain protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: tai:Taci_1362 GntR domain protein; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR domain protein.
 
     0.704
Tlie_0022
PFAM: Saccharopine dehydrogenase; COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: kko:Kkor_1137 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: Saccharopine dehydrogenase.
  
     0.625
Tlie_0157
PFAM: Saccharopine dehydrogenase; COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: dat:HRM2_15290 saccharopine dehydrogenase-like protein (NADP+, L-glutamate forming); PFAM: Saccharopine dehydrogenase; SPTR: Saccharopine dehydrogenase-like protein (NADP+, L-glutamate forming).
  
     0.526
Tlie_1578
PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG3090 TRAP-type C4-dicarboxylate transport system small permease component; KEGG: tai:Taci_1442 TRAP-type C4-dicarboxylate transport system small permease component-like protein; SPTR: TRAP-type C4-dicarboxylate transport system small permease component-like protein.
  
     0.522
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.