STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1676Protein of unknown function DUF112 transmembrane; PFAM: Tripartite tricarboxylate transporter TctA family; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: bhy:BHWA1_02095 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative uncharacterized protein. (495 aa)    
Predicted Functional Partners:
Tlie_1674
Putative lipoprotein; PFAM: Tripartite tricarboxylate transporter family receptor; COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: bcg:BCG9842_B4344 putative lipoprotein; SPTR: Putative uncharacterized protein.
  
 0.985
Tlie_1675
Hypothetical protein; PFAM: Tripartite tricarboxylate transporter TctB family; KEGG: bhy:BHWA1_02094 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.931
Tlie_1864
KEGG: oih:OB3269 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.840
Tlie_1677
Aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type; COGs: COG1048 Aconitase A; InterPro IPR006250: IPR001030: IPR000573: IPR018136; KEGG: tai:Taci_0020 aconitate hydratase; PFAM: aconitate hydratase domain-containing protein; SPTR: Putative aconitate hydratase; TIGRFAM: aconitate hydratase.
       0.510
Tlie_1714
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; InterProIPR005467: IPR000014: IPR013767: IPR003594: IPR 004358; KEGG: pth:PTH_1349 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism.
 
     0.461
Tlie_1678
Isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439: IPR001804: IPR019818; KEGG: tai:Taci_0021 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent.
       0.456
Tlie_1680
Citryl-CoA lyase; PFAM: HpcH/HpaI aldolase/citrate lyase family; COGs: COG2301 Citrate lyase beta subunit; InterPro IPR005000: IPR011206; KEGG: tai:Taci_0340 citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; PRIAM: Citryl-CoA lyase; SPTR: Citrate (Pro-3S)-lyase; Belongs to the HpcH/HpaI aldolase family.
       0.450
Tlie_1681
PFAM: Citrate lyase, alpha subunit (CitF); TIGRFAM: citrate lyase, alpha subunit; COGs: COG3051 Citrate lyase alpha subunit; InterPro IPR006472; KEGG: tai:Taci_0024 citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit; PRIAM: Citrate CoA-transferase; SPTR: Citrate lyase, alpha subunit; TIGRFAM: citrate lyase, alpha subunit.
       0.449
Tlie_1679
Citrate lyase subunit gamma; PFAM: Malonate decarboxylase delta subunit (MdcD); TIGRFAM: citrate lyase acyl carrier protein; InterPro IPR006495; KEGG: tai:Taci_0022 citrate lyase subunit gamma; SPTR: Citrate lyase subunit gamma.
       0.446
Tlie_1450
PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: drm:Dred_0416 regulatory proteins, IclR; PFAM: regulatory protein IclR; Transcriptional regulator IclR; SMART: regulatory protein IclR; SPTR: Transcriptional regulator, IclR family.
 
    0.404
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.