STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_16835-carboxymethyl-2-hydroxymuconateDelta- isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: tit:Thit_0222 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase. (253 aa)    
Predicted Functional Partners:
Tlie_0209
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR012408; KEGG: tjr:TherJR_0630 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: CoA-dependent propionaldehyde dehydrogenase.
  
 
 0.609
Tlie_1684
Putative PAS/PAC sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2206 HD-GYP domain; InterProIPR000014: IPR000700: IPR013655: IPR006674: IPR 001610; KEGG: dak:DaAHT2_2363 putative PAS/PAC sensor protein; PFAM: PAS fold-3 domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: PAC repeat-containing protein; PAS domain containing protein; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein.
       0.561
Tlie_0249
PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: tai:Taci_0447 citrate synthase-like protein; PFAM: Citrate synthase; SPTR: Citrate synthase-like protein.
  
  
 0.553
Tlie_1682
PFAM: 'Cold-shock' DNA-binding domain; COGs: COG1278 Cold shock protein; InterPro IPR002059: IPR019844: IPR012156: IPR011129; KEGG: aco:Amico_0349 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: Cold-shock DNA-binding protein family.
  
    0.530
Tlie_1685
Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG2206 HD-GYP domain; InterPro IPR006674; KEGG: kol:Kole_1134 putative PAS/PAC sensor protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Putative PAS/PAC sensor protein.
       0.524
Tlie_1838
PFAM: Prephenate dehydratase; Chorismate mutase type II; COGs: COG0077 Prephenate dehydratase; InterProIPR020822: IPR001086: IPR002912: IPR002701: IPR 008242; KEGG: dtu:Dtur_1641 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Chorismate mutase/prephenate dehydratase.
     
 0.458
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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