STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Tlie_1846PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660: IPR004089; KEGG: tai:Taci_0323 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis protein. (723 aa)    
Predicted Functional Partners:
Tlie_0084
CheA signal transduction histidine kinase; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR004358: IPR008207: IPR003594: IPR002545: IPR 010808: IPR004105: IPR005467; KEGG: tai:Taci_1310 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; P2 response regulator binding domain protein; [...]
 
 0.998
Tlie_0123
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: glo:Glov_2888 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein.
 
 0.995
Tlie_0136
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: tai:Taci_1572 response regulator receiver modulated CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Chemotaxis protein CheV.
 
 0.995
Tlie_0093
MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: tai:Taci_0862 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type.
 0.989
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.986
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
 0.979
Tlie_0097
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: gtn:GTNG_1085 two-component response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Two-component response regulator.
 
 
 0.973
Tlie_1854
PFAM: GGDEF domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR000014: IPR000160: IPR013767; KEGG: tit:Thit_0615 response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; SPTR: Response regulator r [...]
 
 
 0.944
Tlie_0117
CheC, inhibitor of MCP methylation; PFAM: CheC-like family; COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: tai:Taci_1309 CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; SPTR: CheC, inhibitor of MCP methylation.
 
 
 0.741
Tlie_0055
Diguanylate cyclase with PAS/PAC and GAF sensors; PFAM: GAF domain; GGDEF domain; PAS fold; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterProIPR003018: IPR000160: IPR000014: IPR013656: IPR 000700; KEGG: aco:Amico_1621 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein.
  
 
 0.704
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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