STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1852Transporter, NhaC family (TC 2.A.35); PFAM: Na+/H+ antiporter family; TIGRFAM: Na+/H+ antiporter NhaC; COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461: IPR006162: IPR004770; KEGG: tai:Taci_1400 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter NhaC; TIGRFAM: Na+/H+ antiporter NhaC. (490 aa)    
Predicted Functional Partners:
Tlie_1853
Type IV pilus assembly PilZ; PFAM: PilZ domain; InterPro IPR009875; KEGG: cse:Cseg_0159 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: type IV pilus assembly PilZ; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
       0.590
Tlie_1854
PFAM: GGDEF domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR000014: IPR000160: IPR013767; KEGG: tit:Thit_0615 response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; SPTR: Response regulator r [...]
     
 0.468
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
Server load: low (16%) [HD]