node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDM66974.1 | purT | PE36_18514 | PE36_13112 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Putative phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.896 |
hemH | purD | PE36_11252 | PE36_22765 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.993 |
hemH | purE | PE36_11252 | PE36_14945 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Hypothetical phosphoribosylaminoimidazole carboxylase, catalyticsubunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.993 |
hemH | purF | PE36_11252 | PE36_02369 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.977 |
hemH | purH | PE36_11252 | PE36_22760 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.985 |
hemH | purL | PE36_11252 | PE36_20894 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
hemH | purM | PE36_11252 | PE36_21559 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Putative phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.968 |
hemH | purN | PE36_11252 | PE36_21564 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.988 |
hemH | purT | PE36_11252 | PE36_13112 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | Putative phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.945 |
purD | hemH | PE36_22765 | PE36_11252 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.993 |
purD | purE | PE36_22765 | PE36_14945 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Hypothetical phosphoribosylaminoimidazole carboxylase, catalyticsubunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purD | purF | PE36_22765 | PE36_02369 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.998 |
purD | purH | PE36_22765 | PE36_22760 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.997 |
purD | purL | PE36_22765 | PE36_20894 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
purD | purM | PE36_22765 | PE36_21559 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Putative phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.999 |
purD | purN | PE36_22765 | PE36_21564 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purT | PE36_22765 | PE36_13112 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Putative phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.981 |
purD | purU | PE36_22765 | PE36_04803 | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.842 |
purE | hemH | PE36_14945 | PE36_11252 | Hypothetical phosphoribosylaminoimidazole carboxylase, catalyticsubunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.993 |
purE | purD | PE36_14945 | PE36_22765 | Hypothetical phosphoribosylaminoimidazole carboxylase, catalyticsubunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.999 |