STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabH3-oxoacyl-[acyl-carrier-protein] synthase-3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (317 aa)    
Predicted Functional Partners:
SDD16648.1
[acyl-carrier-protein] S-malonyltransferase.
 
 
 0.997
SDD16722.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.996
SDE47087.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 
 0.961
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
 
 0.921
SDD47075.1
acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein.
 
 
 0.901
SDD68667.1
Enoyl-[acyl-carrier-protein] reductase [NADH].
 
 
 0.878
SDD43422.1
3-oxoacyl-[acyl-carrier protein] reductase.
  
 
 0.814
SDD68647.1
3-oxoacyl-[acyl-carrier protein] reductase.
  
 
 0.805
SDE33110.1
3-oxoacyl-[acyl-carrier protein] reductase.
  
 
 0.801
SDD97789.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
   
 
  0.718
Your Current Organism:
Glycomyces harbinensis
NCBI taxonomy Id: 58114
Other names: ATCC 43155, DSM 46494, G. harbinensis, IFO 14487, JCM 7347, NBRC 14487, NRRL 15337, strain LL-DO5139
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.