STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD22310.1Carbonic anhydrase. (252 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.777
SDE45359.1
Sulfate permease, SulP family.
  
 
 0.776
SDD23298.1
Carbonic anhydrase.
  
  
 
0.774
SDD22329.1
Hypothetical protein.
       0.570
SDD22297.1
Exonuclease SbcC.
  
    0.456
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
       0.451
SDD22254.1
Hypothetical protein.
       0.440
SDD47103.1
IMP dehydrogenase.
    
   0.418
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
   0.418
Your Current Organism:
Glycomyces harbinensis
NCBI taxonomy Id: 58114
Other names: ATCC 43155, DSM 46494, G. harbinensis, IFO 14487, JCM 7347, NBRC 14487, NRRL 15337, strain LL-DO5139
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.