STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD37076.1Glutamine synthetase. (450 aa)    
Predicted Functional Partners:
SDE23390.1
Glutamate synthase (NADPH/NADH) large chain.
  
 
 0.976
SDD37123.1
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
  
  
 0.928
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.896
SDD17824.1
Glutamate dehydrogenase.
     
 0.880
SDE51329.1
Nitrite reductase (NADH) large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.874
carA
Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family.
 
 
 0.870
carB
Carbamoyl-phosphate synthase large subunit.
 
 
 0.867
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.864
SDE56508.1
Gamma-glutamyltranspeptidase / glutathione hydrolase.
     
 0.863
SDE51311.1
Nitrite reductase (NADH) small subunit.
     
 0.850
Your Current Organism:
Glycomyces harbinensis
NCBI taxonomy Id: 58114
Other names: ATCC 43155, DSM 46494, G. harbinensis, IFO 14487, JCM 7347, NBRC 14487, NRRL 15337, strain LL-DO5139
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