SIQ87921.1 protein (Microbispora rosea) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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Score

SIQ87921.1

TrbL/VirB6 plasmid conjugal transfer protein. (811 aa)

Predicted Functional Partners:

SIQ87971.1

0.961

SIQ88024.1

0.886

SIQ87842.1

0.867

SIQ87885.1

0.791

SIR14720.1

0.773

SIS17439.1

0.773

SIR36194.1

0.771

SIR44034.1

0.771

SIS06042.1

0.766

SIQ86792.1

0.765

Your Current Organism:

Microbispora rosea

NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SIQ86792.1	SIQ87921.1	SAMN05421833_104128	SAMN05421833_104158	Sigma-70, region 4.	TrbL/VirB6 plasmid conjugal transfer protein.	0.765
SIQ86792.1	SIQ88024.1	SAMN05421833_104128	SAMN05421833_104160	Sigma-70, region 4.	MinD-like ATPase involved in chromosome partitioning or flagellar assembly.	0.455
SIQ86792.1	SIR14720.1	SAMN05421833_104128	SAMN05421833_106164	Sigma-70, region 4.	Hypothetical protein.	0.676
SIQ86792.1	SIR36194.1	SAMN05421833_104128	SAMN05421833_10898	Sigma-70, region 4.	Hypothetical protein.	0.770
SIQ86792.1	SIR44034.1	SAMN05421833_104128	SAMN05421833_10943	Sigma-70, region 4.	Nuclease-related domain-containing protein.	0.698
SIQ86792.1	SIS06042.1	SAMN05421833_104128	SAMN05421833_12547	Sigma-70, region 4.	Helix-turn-helix.	0.767
SIQ86792.1	SIS17439.1	SAMN05421833_104128	SAMN05421833_1345	Sigma-70, region 4.	Sulfotransferase family protein.	0.653
SIQ87842.1	SIQ87885.1	SAMN05421833_104156	SAMN05421833_104157	NlpC/P60 family protein.	Hypothetical protein.	0.766
SIQ87842.1	SIQ87921.1	SAMN05421833_104156	SAMN05421833_104158	NlpC/P60 family protein.	TrbL/VirB6 plasmid conjugal transfer protein.	0.867
SIQ87842.1	SIQ87971.1	SAMN05421833_104156	SAMN05421833_104159	NlpC/P60 family protein.	AAA-like domain-containing protein.	0.866
SIQ87842.1	SIQ88024.1	SAMN05421833_104156	SAMN05421833_104160	NlpC/P60 family protein.	MinD-like ATPase involved in chromosome partitioning or flagellar assembly.	0.719
SIQ87885.1	SIQ87842.1	SAMN05421833_104157	SAMN05421833_104156	Hypothetical protein.	NlpC/P60 family protein.	0.766
SIQ87885.1	SIQ87921.1	SAMN05421833_104157	SAMN05421833_104158	Hypothetical protein.	TrbL/VirB6 plasmid conjugal transfer protein.	0.791
SIQ87885.1	SIQ87971.1	SAMN05421833_104157	SAMN05421833_104159	Hypothetical protein.	AAA-like domain-containing protein.	0.783
SIQ87885.1	SIQ88024.1	SAMN05421833_104157	SAMN05421833_104160	Hypothetical protein.	MinD-like ATPase involved in chromosome partitioning or flagellar assembly.	0.691
SIQ87921.1	SIQ86792.1	SAMN05421833_104158	SAMN05421833_104128	TrbL/VirB6 plasmid conjugal transfer protein.	Sigma-70, region 4.	0.765
SIQ87921.1	SIQ87842.1	SAMN05421833_104158	SAMN05421833_104156	TrbL/VirB6 plasmid conjugal transfer protein.	NlpC/P60 family protein.	0.867
SIQ87921.1	SIQ87885.1	SAMN05421833_104158	SAMN05421833_104157	TrbL/VirB6 plasmid conjugal transfer protein.	Hypothetical protein.	0.791
SIQ87921.1	SIQ87971.1	SAMN05421833_104158	SAMN05421833_104159	TrbL/VirB6 plasmid conjugal transfer protein.	AAA-like domain-containing protein.	0.961
SIQ87921.1	SIQ88024.1	SAMN05421833_104158	SAMN05421833_104160	TrbL/VirB6 plasmid conjugal transfer protein.	MinD-like ATPase involved in chromosome partitioning or flagellar assembly.	0.886

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Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.805

expected number of edges:

12

PPI enrichment p-value:

1.44e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000271

Polysaccharide biosynthetic process

6 of 58

1.32

1.38

8.66e-05

GO:0009059

Macromolecule biosynthetic process

9 of 230

0.9

0.85

7.05e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016740

Transferase activity

9 of 397

0.66

0.49

0.0041

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016020

Membrane

9 of 617

0.47

0.31

0.0342

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1869

Bacterial sugar transferase, and NUBPL iron-transfer P-loop NTPase

4 of 11

1.86

2.07

3.46e-05

CL:1871

Bacterial sugar transferase, and NUBPL iron-transfer P-loop NTPase

3 of 6

2.0

1.75

0.00033

CL:1863

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Bacterial sugar transferase

6 of 58

1.32

1.5

2.23e-05

CL:1864

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Bacterial sugar transferase

5 of 45

1.35

1.41

9.97e-05

CL:1859

Carbohydrate metabolic process, and Transferase

9 of 156

1.06

1.23

1.29e-06

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0808

Transferase

10 of 332

0.78

0.75

1.10e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02397

Bacterial sugar transferase

4 of 6

2.13

2.47

1.09e-05

PF00535

Glycosyl transferase family 2

5 of 14

1.86

2.43

3.75e-06

PF13727

CoA-binding domain

2 of 2

2.3

1.0

0.0144

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