STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR25232.13' terminal RNA ribose 2'-O-methyltransferase Hen1. (478 aa)    
Predicted Functional Partners:
SIR25258.1
Polynucleotide kinase-phosphatase.
 
   0.978
SIR55926.1
4-methylaminobutanoate oxidase (formaldehyde-forming); Belongs to the GcvT family.
   
  0.728
SIS18756.1
Dimethylglycine oxidase; Belongs to the GcvT family.
   
  0.728
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
  0.658
SIR01029.1
Protoporphyrin IX magnesium-chelatase.
  
 0.636
cysC
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate.
    
 0.600
SIQ70310.1
Hypothetical protein.
 
     0.536
SIR63938.1
Methyltransferase domain-containing protein.
  
 0.518
SIR25201.1
Probable F420-dependent oxidoreductase, Rv1855c family.
       0.491
SIS09942.1
Predicted kinase.
   
   0.463
Your Current Organism:
Microbispora rosea
NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.