STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR22470.1Response regulator receiver domain-containing protein. (140 aa)    
Predicted Functional Partners:
SIR48195.1
Signal transduction histidine kinase.
   
 0.835
SIR65464.1
GAF sensor hybrid histidine kinase.
   
 0.835
SIS25243.1
PAS/PAC sensor signal transduction histidine kinase.
   
 0.763
SIR22417.1
Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
 0.679
SIR78840.1
PAS domain S-box-containing protein.
  
 0.556
SIS22951.1
PAS domain S-box-containing protein.
   
 0.537
SIR22441.1
Hypothetical protein.
       0.526
SIR90934.1
Signal transduction histidine kinase.
   
  0.510
SIS23881.1
Regulatory protein, luxR family.
  
  
  0.471
SIR00161.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
  0.445
Your Current Organism:
Microbispora rosea
NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea
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