SIR44625.1 protein (Microbispora rosea) - STRING interaction network

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Score

SIR44625.1

50S ribosome-binding GTPase. (543 aa)

Predicted Functional Partners:

rplK

0.926

rplC

0.916

rplD

0.915

rplS

0.914

rplM

0.913

rplU

0.912

rplQ

0.911

rplT

0.911

rpmA

0.911

rplV

0.909

Your Current Organism:

Microbispora rosea

NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SIR44625.1	rplC	SAMN05421833_10967	SAMN05421833_1028	50S ribosome-binding GTPase.	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.916
SIR44625.1	rplD	SAMN05421833_10967	SAMN05421833_1029	50S ribosome-binding GTPase.	Large subunit ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.915
SIR44625.1	rplK	SAMN05421833_10967	SAMN05421833_119184	50S ribosome-binding GTPase.	LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.926
SIR44625.1	rplM	SAMN05421833_10967	SAMN05421833_10244	50S ribosome-binding GTPase.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.913
SIR44625.1	rplQ	SAMN05421833_10967	SAMN05421833_10238	50S ribosome-binding GTPase.	LSU ribosomal protein L17P.	0.911
SIR44625.1	rplS	SAMN05421833_10967	SAMN05421833_108196	50S ribosome-binding GTPase.	LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.914
SIR44625.1	rplT	SAMN05421833_10967	SAMN05421833_10310	50S ribosome-binding GTPase.	Large subunit ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.911
SIR44625.1	rplU	SAMN05421833_10967	SAMN05421833_10619	50S ribosome-binding GTPase.	LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.912
SIR44625.1	rplV	SAMN05421833_10967	SAMN05421833_10213	50S ribosome-binding GTPase.	LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.909
SIR44625.1	rpmA	SAMN05421833_10967	SAMN05421833_10620	50S ribosome-binding GTPase.	LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family.	0.911
rplC	SIR44625.1	SAMN05421833_1028	SAMN05421833_10967	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosome-binding GTPase.	0.916
rplC	rplD	SAMN05421833_1028	SAMN05421833_1029	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	Large subunit ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.999
rplC	rplK	SAMN05421833_1028	SAMN05421833_119184	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.999
rplC	rplM	SAMN05421833_1028	SAMN05421833_10244	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rplC	rplQ	SAMN05421833_1028	SAMN05421833_10238	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	LSU ribosomal protein L17P.	0.999
rplC	rplS	SAMN05421833_1028	SAMN05421833_108196	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.999
rplC	rplT	SAMN05421833_1028	SAMN05421833_10310	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	Large subunit ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.999
rplC	rplU	SAMN05421833_1028	SAMN05421833_10619	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.998
rplC	rplV	SAMN05421833_1028	SAMN05421833_10213	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rplC	rpmA	SAMN05421833_1028	SAMN05421833_10620	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family.	0.999