Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIR86229.1Hypothetical protein. (403 aa)    
Predicted Functional Partners:
SIQ30661.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.922
SIQ76690.1
2-oxoisovalerate dehydrogenase E1 component.
   
 0.820
SIR86210.1
4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family.
    
 0.817
SIR86220.1
Hypothetical protein.
       0.808
SIR81940.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.774
SIR86164.1
Predicted dithiol-disulfide isomerase, DsbA family.
       0.774
SIR86176.1
Purine-cytosine permease; Belongs to the purine-cytosine permease (2.A.39) family.
       0.773
SIR86189.1
Nitrite reductase (NADH) small subunit.
       0.773
SIR86199.1
Iron-containing redox enzyme.
       0.773
SIR99497.1
L-aspartate oxidase /nicotinate-nucleotide pyrophosphorylase [carboxylating]; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 
 0.771
Your Current Organism:
Microbispora rosea
NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.