STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR94430.1Tfp pilus assembly protein PilF. (489 aa)    
Predicted Functional Partners:
ribBA
GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.789
SIR88879.1
Tetratricopeptide repeat-containing protein.
 
  
  0.759
SIS12733.1
Tetratricopeptide repeat-containing protein.
 
  
  0.756
SIS25243.1
PAS/PAC sensor signal transduction histidine kinase.
    
 0.731
SIR48195.1
Signal transduction histidine kinase.
     
 0.689
SIR65464.1
GAF sensor hybrid histidine kinase.
     
 0.689
SIR94416.1
Ubiquinone/menaquinone biosynthesis C-methylase UbiE.
    
  0.540
SIS12741.1
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family.
 
  
  0.534
SIR94444.1
Carboxymethylenebutenolidase/hypothetical protein.
       0.533
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.532
Your Current Organism:
Microbispora rosea
NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.