STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS16453.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (235 aa)    
Predicted Functional Partners:
SIS00762.1
Arylsulfatase A.
 
   0.934
SIS00772.1
Arylsulfatase A.
 
   0.930
SIR70193.1
Arylsulfatase A.
 
   0.919
SIS16440.1
Two-component system, OmpR family, response regulator VanR.
       0.773
SIS16447.1
Two-component system, OmpR family, sensor histidine kinase VanS.
       0.773
SIR63485.1
L-histidine Nalpha-methyltransferase.
  
 
 0.676
egtD
L-histidine Nalpha-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
 
 0.676
SIS16434.1
Putative ABC transport system ATP-binding protein.
  
    0.562
SIS16427.1
Putative ABC transport system permease protein.
       0.549
SIR27155.1
Glutamine amidotransferase.
  
 
  0.536
Your Current Organism:
Microbispora rosea
NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.