STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (372 aa)    
Predicted Functional Partners:
SIQ17706.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
SIQ65817.1
Xylulose-5-phosphate/fructose-6-phosphate phosphoketolase.
 
 0.950
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.921
SIR71119.1
Isocitrate lyase.
   
  
 0.905
SIR54154.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.873
SIQ97314.1
acetyl-CoA synthetase.
   
 
 0.851
SIR85292.1
Malate synthase; Belongs to the malate synthase family.
   
 
 0.757
SIR01425.1
Pyruvate dehydrogenase (quinone)/pyruvate oxidase; Belongs to the TPP enzyme family.
    
 0.752
SIS04935.1
Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family.
    
 0.752
SIS18536.1
Phenazine biosynthesis protein PhzF family.
       0.752
Your Current Organism:
Microbispora rosea
NCBI taxonomy Id: 58117
Other names: ATCC 12950, DSM 43839, IFO 14044, JCM 3006, M. rosea, NBRC 14044, NRRL B-2632, VKM Ac-634, Waksmania rosea
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.