STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SET67806.1c-di-AMP phosphodiesterase, consists of a GGDEF-like and DHH domains; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (686 aa)    
Predicted Functional Partners:
rplI
Large subunit ribosomal protein L9; Binds to the 23S rRNA.
 
  
 0.940
SET67745.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
  
 0.872
tmcAL
Predicted nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
     0.660
SEU31330.1
tRNA (adenine22-N1)-methyltransferase.
  
     0.644
SET76130.1
tRNA1Val (adenine37-N6)-methyltransferase.
  
     0.618
polC
DNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.614
SET58422.1
Energy-coupling factor transport system permease protein.
  
     0.587
SEU29873.1
Putative HD superfamily hydrolase of NAD metabolism.
  
   
 0.572
ecfA
Energy-coupling factor transport system ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
     0.571
SET74055.1
DnaD and phage-associated domain-containing protein.
 
     0.563
Your Current Organism:
Desulfotomaculum guttoideum
NCBI taxonomy Id: 58134
Other names: DSM 4024, [. guttoideum, [Desulfotomaculum] guttoideum
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