node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMG71871.1 | dsrH | AL531_16760 | AL531_16765 | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | Sulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.992 |
AMG71871.1 | tusA | AL531_16760 | AL531_12830 | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | tRNA 2-thiouridine(34) synthase TusA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. | 0.434 |
AMG71871.1 | tusD | AL531_16760 | AL531_16755 | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | tRNA 2-thiouridine(34) synthase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | 0.999 |
AMG71871.1 | tusE | AL531_16760 | AL531_03050 | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | Sulfur relay protein TusE; Part of a sulfur-relay system. | 0.819 |
AMG72283.1 | tusE | AL531_07550 | AL531_03050 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfur relay protein TusE; Part of a sulfur-relay system. | 0.490 |
dsrH | AMG71871.1 | AL531_16765 | AL531_16760 | Sulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | 0.992 |
dsrH | tusD | AL531_16765 | AL531_16755 | Sulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | tRNA 2-thiouridine(34) synthase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | 0.992 |
dsrH | tusE | AL531_16765 | AL531_03050 | Sulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Sulfur relay protein TusE; Part of a sulfur-relay system. | 0.804 |
mnmA | tusE | AL531_09205 | AL531_03050 | tRNA 2-thiouridine(34) synthase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. | Sulfur relay protein TusE; Part of a sulfur-relay system. | 0.937 |
tusA | AMG71871.1 | AL531_12830 | AL531_16760 | tRNA 2-thiouridine(34) synthase TusA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | 0.434 |
tusA | tusD | AL531_12830 | AL531_16755 | tRNA 2-thiouridine(34) synthase TusA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. | tRNA 2-thiouridine(34) synthase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | 0.973 |
tusA | tusE | AL531_12830 | AL531_03050 | tRNA 2-thiouridine(34) synthase TusA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. | Sulfur relay protein TusE; Part of a sulfur-relay system. | 0.418 |
tusD | AMG71871.1 | AL531_16755 | AL531_16760 | tRNA 2-thiouridine(34) synthase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | 0.999 |
tusD | dsrH | AL531_16755 | AL531_16765 | tRNA 2-thiouridine(34) synthase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Sulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.992 |
tusD | tusA | AL531_16755 | AL531_12830 | tRNA 2-thiouridine(34) synthase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | tRNA 2-thiouridine(34) synthase TusA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. | 0.973 |
tusD | tusE | AL531_16755 | AL531_03050 | tRNA 2-thiouridine(34) synthase TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Sulfur relay protein TusE; Part of a sulfur-relay system. | 0.984 |
tusE | AMG71871.1 | AL531_03050 | AL531_16760 | Sulfur relay protein TusE; Part of a sulfur-relay system. | Sulfur relay protein TusC/DsrF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family. | 0.819 |
tusE | AMG72283.1 | AL531_03050 | AL531_07550 | Sulfur relay protein TusE; Part of a sulfur-relay system. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.490 |
tusE | dsrH | AL531_03050 | AL531_16765 | Sulfur relay protein TusE; Part of a sulfur-relay system. | Sulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.804 |
tusE | mnmA | AL531_03050 | AL531_09205 | Sulfur relay protein TusE; Part of a sulfur-relay system. | tRNA 2-thiouridine(34) synthase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. | 0.937 |