node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMG70200.1 | AMG72129.1 | AL531_07520 | AL531_18225 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |
AMG70200.1 | nfuA | AL531_07520 | AL531_15085 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.462 |
AMG70200.1 | nifU | AL531_07520 | AL531_03900 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.931 |
AMG70200.1 | sufA | AL531_07520 | AL531_07540 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Fe-S cluster assembly scaffold SufA; Functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | 0.720 |
AMG70200.1 | sufB | AL531_07520 | AL531_07535 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | FeS cluster assembly protein SufB; With SufCD activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
AMG70200.1 | sufC | AL531_07520 | AL531_07530 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Fe-S cluster assembly ATPase SufC; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
AMG70200.1 | sufD | AL531_07520 | AL531_07525 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Fe-S cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
AMG70200.1 | sufE | AL531_07520 | AL531_07515 | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | Cysteine desufuration protein SufE; Acts with SufS to catalyze the formation of L-alanine from L-cysteine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |
AMG72129.1 | AMG70200.1 | AL531_18225 | AL531_07520 | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine sulfinate desulfinase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. | 0.749 |
AMG72129.1 | AMG72130.1 | AL531_18225 | AL531_18230 | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.944 |
AMG72129.1 | sufB | AL531_18225 | AL531_07535 | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | FeS cluster assembly protein SufB; With SufCD activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.710 |
AMG72129.1 | sufC | AL531_18225 | AL531_07530 | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly ATPase SufC; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.638 |
AMG72129.1 | sufD | AL531_18225 | AL531_07525 | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.621 |
AMG72130.1 | AMG72129.1 | AL531_18230 | AL531_18225 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S metabolism protein SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.944 |
AMG72130.1 | nfuA | AL531_18230 | AL531_15085 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.462 |
AMG72130.1 | nifU | AL531_18230 | AL531_03900 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.931 |
AMG72130.1 | sufB | AL531_18230 | AL531_07535 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | FeS cluster assembly protein SufB; With SufCD activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.938 |
AMG72130.1 | sufC | AL531_18230 | AL531_07530 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly ATPase SufC; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.942 |
AMG72130.1 | sufD | AL531_18230 | AL531_07525 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
AMG72130.1 | sufE | AL531_18230 | AL531_07515 | Cysteine sulfinate desulfinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desufuration protein SufE; Acts with SufS to catalyze the formation of L-alanine from L-cysteine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |