STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PBANKA_0402300Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (443 aa)    
Predicted Functional Partners:
PBANKA_1104200
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial, putative.
 
 0.997
PBANKA_1446900
Dihydrolipoyl dehydrogenase.
 
 0.997
PBANKA_1411100
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 0.997
PBANKA_0714900
Dihydrolipoyl dehydrogenase, apicoplast, putative; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.996
PBANKA_0710100
2-oxoglutarate dehydrogenase E1 component, putative.
  
 0.975
PBANKA_1310100
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.935
PBANKA_1126500
Acetyl-CoA synthetase, putative.
  
 
 0.931
PBANKA_0915500
Glycine cleavage system H protein, putative.
  
 0.866
PBANKA_0824700
Thioredoxin reductase, putative.
 
 0.856
PBANKA_1023400
Glutathione reductase, putative.
 
 0.856
Your Current Organism:
Plasmodium berghei
NCBI taxonomy Id: 5823
Other names: P. berghei ANKA, Plasmodium berghei (strain ANKA), Plasmodium berghei ANKA, Plasmodium berghei str. ANKA, Plasmodium berghei strain ANKA
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