STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PBANKA_07101002-oxoglutarate dehydrogenase E1 component, putative. (1038 aa)    
Predicted Functional Partners:
PBANKA_1419100
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
 0.999
PBANKA_0714900
Dihydrolipoyl dehydrogenase, apicoplast, putative; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.996
PBANKA_1446900
Dihydrolipoyl dehydrogenase.
  
 0.996
PBANKA_0505000
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.988
PBANKA_1419000
Uncharacterized protein.
  
 0.988
PBANKA_1358600
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 
 0.986
PBANKA_1013200
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.982
PBANKA_0402300
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.975
PBANKA_0938500
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.973
PBANKA_0518200
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
 
 
 0.956
Your Current Organism:
Plasmodium berghei
NCBI taxonomy Id: 5823
Other names: P. berghei ANKA, Plasmodium berghei (strain ANKA), Plasmodium berghei ANKA, Plasmodium berghei str. ANKA, Plasmodium berghei strain ANKA
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