STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PBANKA_0910600Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...] (125 aa)    
Predicted Functional Partners:
PBANKA_1141200
Ubiquitin-activating enzyme, putative.
    
 0.999
PBANKA_0110900
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
    
 0.866
PBANKA_0315600
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
  
 0.681
PBANKA_1442500
Elongator complex protein 3, putative.
    
 
 0.655
PBANKA_0713800
NEDD8-activating enzyme E1 catalytic subunit, putative.
    
 
 0.604
PBANKA_0605000
Rhodanese like protein, putative.
      
 0.593
PBANKA_0809900
tRNA pseudouridine synthase.
    
 
 0.544
PBANKA_1034700
Multifunctional methyltransferase subunit TRM112, putative.
   
  
 0.541
PBANKA_0610200
DNA replication licensing factor MCM5, putative; Belongs to the MCM family.
      
 0.504
PBANKA_0509500
Uncharacterized protein.
    
 
 0.496
Your Current Organism:
Plasmodium berghei
NCBI taxonomy Id: 5823
Other names: P. berghei ANKA, Plasmodium berghei (strain ANKA), Plasmodium berghei ANKA, Plasmodium berghei str. ANKA, Plasmodium berghei strain ANKA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.