STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hbal_0015TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ccs:CCNA_03821 exodeoxyribonuclease III. (269 aa)    
Predicted Functional Partners:
Hbal_1335
TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: pla:Plav_3018 exodeoxyribonuclease III Xth.
  
  
 
0.921
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 0.858
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.851
Hbal_0433
Transcriptional regulator, AraC family; PFAM: Ada metal-binding domain protein; AlkA domain protein; HhH-GPD family protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; HhH-GPD family protein; KEGG: pzu:PHZ_c2256 transcriptional regulator, AraC family.
   
 0.846
Hbal_1063
HhH-GPD family protein; Adenine glycosylase active on G-A mispairs.
    
 0.786
Hbal_3037
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.768
hfq
RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
    
 
 0.684
Hbal_1630
KEGG: sit:TM1040_3592 DNA polymerase III subunit delta'.
   
  0.568
Hbal_0260
PFAM: pseudouridine synthase; RNA-binding S4 domain protein; KEGG: pzu:PHZ_c2300 ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.
  
    0.556
Hbal_0994
PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; KEGG: ret:RHE_CH00835 pseudouridylate synthase, subunit B protein; Belongs to the pseudouridine synthase RsuA family.
  
    0.556
Your Current Organism:
Hirschia baltica
NCBI taxonomy Id: 582402
Other names: H. baltica ATCC 49814, Hirschia baltica ATCC 49814, Hirschia baltica DSM 5838, Hirschia baltica str. ATCC 49814, Hirschia baltica strain ATCC 49814
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.