node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hbal_0070 | Hbal_0072 | Hbal_0070 | Hbal_0072 | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.871 |
Hbal_0070 | Hbal_0076 | Hbal_0070 | Hbal_0076 | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | 0.469 |
Hbal_0070 | gpsA | Hbal_0070 | Hbal_0075 | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pzu:PHZ_c3407 glycerol-3-phosphate dehydrogenase (NAD+). | 0.477 |
Hbal_0070 | hemC | Hbal_0070 | Hbal_0073 | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.692 |
Hbal_0070 | tsaD | Hbal_0070 | Hbal_0074 | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.574 |
Hbal_0072 | Hbal_0070 | Hbal_0072 | Hbal_0070 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | 0.871 |
Hbal_0072 | Hbal_0076 | Hbal_0072 | Hbal_0076 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | 0.591 |
Hbal_0072 | gpsA | Hbal_0072 | Hbal_0075 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pzu:PHZ_c3407 glycerol-3-phosphate dehydrogenase (NAD+). | 0.526 |
Hbal_0072 | hemC | Hbal_0072 | Hbal_0073 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
Hbal_0072 | tsaD | Hbal_0072 | Hbal_0074 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.711 |
Hbal_0076 | Hbal_0070 | Hbal_0076 | Hbal_0070 | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | 0.469 |
Hbal_0076 | Hbal_0072 | Hbal_0076 | Hbal_0072 | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.591 |
Hbal_0076 | gpsA | Hbal_0076 | Hbal_0075 | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pzu:PHZ_c3407 glycerol-3-phosphate dehydrogenase (NAD+). | 0.790 |
Hbal_0076 | hemC | Hbal_0076 | Hbal_0073 | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.478 |
Hbal_0076 | hisE | Hbal_0076 | Hbal_3139 | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: bbt:BBta_0141 phosphoribosyl-ATP pyrophosphatase. | 0.414 |
Hbal_0076 | tsaD | Hbal_0076 | Hbal_0074 | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.602 |
gpsA | Hbal_0070 | Hbal_0075 | Hbal_0070 | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pzu:PHZ_c3407 glycerol-3-phosphate dehydrogenase (NAD+). | PFAM: HemY domain protein; KEGG: pzu:PHZ_c3402 hypothetical protein. | 0.477 |
gpsA | Hbal_0072 | Hbal_0075 | Hbal_0072 | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pzu:PHZ_c3407 glycerol-3-phosphate dehydrogenase (NAD+). | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.526 |
gpsA | Hbal_0076 | Hbal_0075 | Hbal_0076 | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pzu:PHZ_c3407 glycerol-3-phosphate dehydrogenase (NAD+). | PFAM: YCII-related; KEGG: bcs:BCAN_A1933 YciI-like protein. | 0.790 |
gpsA | hemC | Hbal_0075 | Hbal_0073 | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pzu:PHZ_c3407 glycerol-3-phosphate dehydrogenase (NAD+). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.488 |