STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hbal_0839PFAM: aminotransferase class IV; KEGG: oca:OCAR_5218 aminotransferase, class IV. (269 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.967
ilvD
KEGG: pla:Plav_3010 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.967
Hbal_0838
KEGG: cak:Caul_4201 para-aminobenzoate synthase component I; TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein.
  
 0.949
Hbal_2132
PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; KEGG: ccs:CCNA_02164 leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
 
 0.945
Hbal_1615
PFAM: Transketolase central region; Transketolase domain protein; KEGG: mlo:mll4472 2-oxoisovalerate dehydrogenase (beta subunit).
   
 0.918
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.914
Hbal_1614
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: dehydrogenase E1 component; KEGG: rle:pRL100303 putative 2-oxoisovalerate dehydrogenase.
   
 
 0.908
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.907
Hbal_1019
Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.900
Hbal_1864
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: cak:Caul_3015 homoserine dehydrogenase.
  
 
 0.883
Your Current Organism:
Hirschia baltica
NCBI taxonomy Id: 582402
Other names: H. baltica ATCC 49814, Hirschia baltica ATCC 49814, Hirschia baltica DSM 5838, Hirschia baltica str. ATCC 49814, Hirschia baltica strain ATCC 49814
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