node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hbal_0246 | Hbal_2154 | Hbal_0246 | Hbal_2154 | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: ret:RHE_CH03790 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.946 |
Hbal_0246 | Hbal_2161 | Hbal_0246 | Hbal_2161 | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: ret:RHE_CH03790 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | 0.915 |
Hbal_0246 | Hbal_2162 | Hbal_0246 | Hbal_2162 | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: ret:RHE_CH03790 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.925 |
Hbal_0246 | cobD | Hbal_0246 | Hbal_2160 | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: ret:RHE_CH03790 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.919 |
Hbal_0246 | cobQ | Hbal_0246 | Hbal_2159 | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: ret:RHE_CH03790 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.921 |
Hbal_2154 | Hbal_0246 | Hbal_2154 | Hbal_0246 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: ret:RHE_CH03790 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.946 |
Hbal_2154 | Hbal_2161 | Hbal_2154 | Hbal_2161 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | 0.982 |
Hbal_2154 | Hbal_2162 | Hbal_2154 | Hbal_2162 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.970 |
Hbal_2154 | cobD | Hbal_2154 | Hbal_2160 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.985 |
Hbal_2154 | cobQ | Hbal_2154 | Hbal_2159 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
Hbal_2154 | cobT | Hbal_2154 | Hbal_2151 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.808 |
Hbal_2161 | Hbal_0246 | Hbal_2161 | Hbal_0246 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: ret:RHE_CH03790 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.915 |
Hbal_2161 | Hbal_2154 | Hbal_2161 | Hbal_2154 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.982 |
Hbal_2161 | Hbal_2162 | Hbal_2161 | Hbal_2162 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.974 |
Hbal_2161 | cobD | Hbal_2161 | Hbal_2160 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.996 |
Hbal_2161 | cobQ | Hbal_2161 | Hbal_2159 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.999 |
Hbal_2161 | cobT | Hbal_2161 | Hbal_2151 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.819 |
Hbal_2161 | hisB | Hbal_2161 | Hbal_3133 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: cak:Caul_5045 imidazoleglycerol-phosphate dehydratase. | 0.837 |
Hbal_2161 | hisD | Hbal_2161 | Hbal_1769 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.835 |
Hbal_2161 | hisH | Hbal_2161 | Hbal_3134 | TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: rpc:RPC_3743 aminotransferase, class I and II. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.839 |