node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFK91993.1 | SFK92037.1 | SAMN05192579_10918 | SAMN05192579_10920 | Hypothetical protein. | Predicted hydrolase of the alpha/beta-hydrolase fold. | 0.605 |
SFK91993.1 | SFK92073.1 | SAMN05192579_10918 | SAMN05192579_10921 | Hypothetical protein. | N-acetylmuramoyl-L-alanine amidase. | 0.464 |
SFK91993.1 | rlmL | SAMN05192579_10918 | SAMN05192579_10919 | Hypothetical protein. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.658 |
SFK92037.1 | SFK91993.1 | SAMN05192579_10920 | SAMN05192579_10918 | Predicted hydrolase of the alpha/beta-hydrolase fold. | Hypothetical protein. | 0.605 |
SFK92037.1 | SFK92073.1 | SAMN05192579_10920 | SAMN05192579_10921 | Predicted hydrolase of the alpha/beta-hydrolase fold. | N-acetylmuramoyl-L-alanine amidase. | 0.656 |
SFK92037.1 | rlmL | SAMN05192579_10920 | SAMN05192579_10919 | Predicted hydrolase of the alpha/beta-hydrolase fold. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.834 |
SFK92073.1 | SFK91993.1 | SAMN05192579_10921 | SAMN05192579_10918 | N-acetylmuramoyl-L-alanine amidase. | Hypothetical protein. | 0.464 |
SFK92073.1 | SFK92037.1 | SAMN05192579_10921 | SAMN05192579_10920 | N-acetylmuramoyl-L-alanine amidase. | Predicted hydrolase of the alpha/beta-hydrolase fold. | 0.656 |
SFK92073.1 | rlmL | SAMN05192579_10921 | SAMN05192579_10919 | N-acetylmuramoyl-L-alanine amidase. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.629 |
birA | rlmL | SAMN05192579_10331 | SAMN05192579_10919 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.576 |
mltG | rlmL | SAMN05192579_101272 | SAMN05192579_10919 | UPF0755 protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.566 |
pnp | pyrG | SAMN05192579_101298 | SAMN05192579_10778 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.774 |
pnp | rapA | SAMN05192579_101298 | SAMN05192579_11242 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.858 |
pnp | rlmL | SAMN05192579_101298 | SAMN05192579_10919 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.608 |
pnp | typA | SAMN05192579_101298 | SAMN05192579_12044 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | GTP-binding protein. | 0.436 |
pnp | uppS | SAMN05192579_101298 | SAMN05192579_109105 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.678 |
pyrG | pnp | SAMN05192579_10778 | SAMN05192579_101298 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.774 |
pyrG | rlmL | SAMN05192579_10778 | SAMN05192579_10919 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.572 |
pyrG | uppS | SAMN05192579_10778 | SAMN05192579_109105 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.624 |
rapA | pnp | SAMN05192579_11242 | SAMN05192579_101298 | ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.858 |