| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACT50959.1 | ACT50962.1 | Msip34_1714 | Msip34_1717 | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | KEGG: mfa:Mfla_1621 hypothetical protein. | 0.778 |
| ACT50959.1 | ACT50963.1 | Msip34_1714 | Msip34_1718 | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | 0.741 |
| ACT50959.1 | hisS | Msip34_1714 | Msip34_1715 | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | KEGG: mfa:Mfla_1619 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. | 0.788 |
| ACT50959.1 | ispG | Msip34_1714 | Msip34_1716 | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.780 |
| ACT50959.1 | ndk | Msip34_1714 | Msip34_1720 | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.749 |
| ACT50959.1 | rlmN | Msip34_1714 | Msip34_1719 | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.746 |
| ACT50962.1 | ACT50959.1 | Msip34_1717 | Msip34_1714 | KEGG: mfa:Mfla_1621 hypothetical protein. | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | 0.778 |
| ACT50962.1 | ACT50963.1 | Msip34_1717 | Msip34_1718 | KEGG: mfa:Mfla_1621 hypothetical protein. | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | 0.833 |
| ACT50962.1 | hisS | Msip34_1717 | Msip34_1715 | KEGG: mfa:Mfla_1621 hypothetical protein. | KEGG: mfa:Mfla_1619 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. | 0.820 |
| ACT50962.1 | ispG | Msip34_1717 | Msip34_1716 | KEGG: mfa:Mfla_1621 hypothetical protein. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.912 |
| ACT50962.1 | ndk | Msip34_1717 | Msip34_1720 | KEGG: mfa:Mfla_1621 hypothetical protein. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.818 |
| ACT50962.1 | rlmN | Msip34_1717 | Msip34_1719 | KEGG: mfa:Mfla_1621 hypothetical protein. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.820 |
| ACT50963.1 | ACT50959.1 | Msip34_1718 | Msip34_1714 | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: mfa:Mfla_1618 ABC transporter related; Belongs to the ABC transporter superfamily. | 0.741 |
| ACT50963.1 | ACT50962.1 | Msip34_1718 | Msip34_1717 | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | KEGG: mfa:Mfla_1621 hypothetical protein. | 0.833 |
| ACT50963.1 | hisS | Msip34_1718 | Msip34_1715 | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | KEGG: mfa:Mfla_1619 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. | 0.786 |
| ACT50963.1 | ispG | Msip34_1718 | Msip34_1716 | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.814 |
| ACT50963.1 | ndk | Msip34_1718 | Msip34_1720 | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.813 |
| ACT50963.1 | rlmN | Msip34_1718 | Msip34_1719 | KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.822 |
| dxr | ispD | Msip34_1405 | Msip34_1182 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.986 |
| dxr | ispF | Msip34_1405 | Msip34_1183 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.865 |
