STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACT50963.1KEGG: mfa:Mfla_1622 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein. (251 aa)    
Predicted Functional Partners:
ACT50962.1
KEGG: mfa:Mfla_1621 hypothetical protein.
  
    0.810
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
    0.800
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.794
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.794
hisS
KEGG: mfa:Mfla_1619 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein.
       0.765
ACT51742.1
PFAM: Fimbrial assembly family protein; KEGG: mfa:Mfla_2460 fimbrial assembly.
  
   
 0.765
ACT51741.1
PFAM: Pilus assembly protein PilO; KEGG: mfa:Mfla_2459 pilus assembly protein, PilO.
  
   
 0.763
ACT51743.1
TIGRFAM: type IV pilus assembly protein PilM; KEGG: mfa:Mfla_2461 type IV pilus assembly protein PilM.
  
   
 0.753
ACT49432.1
PFAM: Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: mfa:Mfla_0188 peptidoglycan-binding LysM.
  
     0.751
ACT51740.1
PFAM: Pilus assembly protein PilP; KEGG: mfa:Mfla_2458 type IV pilus assembly protein PilP.
  
   
 0.750
Your Current Organism:
Methylovorus glucosetrophus
NCBI taxonomy Id: 582744
Other names: M. glucosetrophus SIP3-4, Methylovorus glucosetrophus SIP3-4, Methylovorus glucosetrophus str. SIP3-4, Methylovorus glucosetrophus strain SIP3-4, Methylovorus sp. SIP3-4
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