STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmhASugar isomerase (SIS); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (187 aa)    
Predicted Functional Partners:
hldE
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
  
 0.999
ACT51370.1
TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: mfa:Mfla_0643 D,D-heptose 1,7-bisphosphate phosphatase.
  
 0.989
ACT51555.1
KEGG: mfa:Mfla_2284 phosphoheptose isomerase.
  
  
 
0.912
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.895
ACT51133.1
TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; KEGG: mfa:Mfla_0768 lipopolysaccharide heptosyltransferase II.
 
   
 0.867
ACT51150.1
PFAM: glycosyl transferase family 9; KEGG: noc:Noc_0578 glycosyl transferase family protein.
 
   
 0.742
ACT51134.1
KEGG: mfa:Mfla_0767 hypothetical protein.
       0.717
ACT51152.1
PFAM: glycosyl transferase family 9; KEGG: pla:Plav_1688 glycosyl transferase family protein.
 
   
 0.559
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.510
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
       0.450
Your Current Organism:
Methylovorus glucosetrophus
NCBI taxonomy Id: 582744
Other names: M. glucosetrophus SIP3-4, Methylovorus glucosetrophus SIP3-4, Methylovorus glucosetrophus str. SIP3-4, Methylovorus glucosetrophus strain SIP3-4, Methylovorus sp. SIP3-4
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