Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACT51662.1PFAM: Sarcosine oxidase gamma subunit; KEGG: mfa:Mfla_0455 hypothetical protein. (219 aa)    
Predicted Functional Partners:
ACT51664.1
PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: mfa:Mfla_0453 sarcosine oxidase, delta subunit, heterotetrameric.
 
 0.997
ACT51663.1
PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein barrel; FAD dependent oxidoreductase; KEGG: mfa:Mfla_0454 aminomethyltransferase; Belongs to the GcvT family.
 
  
  0.993
ACT51665.1
PFAM: FAD dependent oxidoreductase; KEGG: mfa:Mfla_0452 FAD dependent oxidoreductase.
 
 0.989
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.949
ACT49905.1
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; biotin/lipoyl attachment domain-containing protein; KEGG: mfa:Mfla_2076 dihydrolipoamide dehydrogenase.
  
 0.942
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 0.892
ACT51660.1
PFAM: glutamine amidotransferase class-II; KEGG: mfa:Mfla_0457 glutamate synthase (NADPH) GltB1 subunit.
 
     0.801
ACT51666.1
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; KEGG: mfa:Mfla_0437 transcriptional regulator.
 
   
 0.785
ACT51697.1
PFAM: amino acid permease-associated region; KEGG: mfa:Mfla_0446 amino acid permease-associated region.
  
  
 0.755
ACT51661.1
TIGRFAM: glutamine synthetase, type III; PFAM: glutamine synthetase catalytic region; KEGG: mfa:Mfla_0456 L-glutamine synthetase.
 
   
 0.754
Your Current Organism:
Methylovorus glucosetrophus
NCBI taxonomy Id: 582744
Other names: M. glucosetrophus SIP3-4, Methylovorus glucosetrophus SIP3-4, Methylovorus glucosetrophus str. SIP3-4, Methylovorus glucosetrophus strain SIP3-4, Methylovorus sp. SIP3-4
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