STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hden_0055KEGG: cwo:Cwoe_3291 drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1. (663 aa)    
Predicted Functional Partners:
Hden_1365
GAF sensor hybrid histidine kinase; KEGG: bja:bll2599 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver.
 
  
 0.656
Hden_2268
PFAM: secretion protein HlyD family protein; KEGG: spl:Spea_2191 secretion protein HlyD family protein.
 
 
 0.603
Hden_2135
PFAM: secretion protein HlyD family protein; KEGG: rhi:NGR_c29530 putative multidrug resistance protein.
 
 
 0.584
Hden_0090
Amino acid adenylation domain protein; KEGG: dma:DMR_01570 putative non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; non-ribosomal peptide synthetase; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; transferase hexapeptide repeat containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.570
Hden_2676
KEGG: nwi:Nwi_0662 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein.
 
 
 0.553
Hden_1803
Transcriptional regulator, ArsR family; KEGG: bmt:BSUIS_A1504 methyltransferase type 11; PFAM: Methyltransferase type 11; regulatory protein ArsR; SMART: regulatory protein ArsR.
  
  
 0.524
Hden_2665
AMP-dependent synthetase and ligase; KEGG: bja:bll2324 acylglycerophosphoethanolamine acyltransferase; PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
     
 0.502
Hden_1421
KEGG: mxa:MXAN_2606 sensor histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
 
  
 0.501
Hden_1766
KEGG: mno:Mnod_4585 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein.
  
  
 0.478
Hden_1066
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-4 domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; KEGG: rfr:Rfer_4387 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
  
  
 0.457
Your Current Organism:
Hyphomicrobium denitrificans ATCC 51888
NCBI taxonomy Id: 582899
Other names: H. denitrificans ATCC 51888, Hyphomicrobium denitrificans str. ATCC 51888, Hyphomicrobium denitrificans strain ATCC 51888
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.