STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Hden_0222Transcriptional regulator of molybdate metabolism, LysR family; PFAM: regulatory protein LysR; KEGG: bja:bll3775 formate dehydrogenase. (358 aa)    
Predicted Functional Partners:
Hden_1439
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 0.944
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.703
Hden_0463
KEGG: atc:AGR_C_4642 molybdate-binding periplasmic protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1.
 
   
 0.664
Hden_0464
Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
   
 0.654
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.645
Hden_0221
PFAM: glycoside hydrolase family 3 domain protein; KEGG: mag:amb1842 beta-glucosidase-related glycosidase.
  
    0.623
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
  
  
 0.586
Hden_1868
PFAM: MOSC domain containing protein; 3-alpha domain protein; KEGG: xau:Xaut_5027 MOSC domain-containing protein.
     
 0.524
Hden_0527
PFAM: Soluble ligand binding domain; KEGG: nhl:Nhal_2430 respiratory-chain NADH dehydrogenase domain 51 kDa subunit.
 
   
 0.496
Hden_2466
Manually curated; TIGRFAM: formate dehydrogenase, alpha subunit; KEGG: azl:AZL_a00170 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region.
 
     0.478
Your Current Organism:
Hyphomicrobium denitrificans ATCC 51888
NCBI taxonomy Id: 582899
Other names: H. denitrificans ATCC 51888, Hyphomicrobium denitrificans str. ATCC 51888, Hyphomicrobium denitrificans strain ATCC 51888
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