STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hden_2002TIGRFAM: pyruvate, phosphate dikinase; KEGG: xau:Xaut_0494 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilizing protein; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family. (908 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.941
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.933
Hden_2644
TIGRFAM: pyruvate kinase; KEGG: smd:Smed_2676 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
 0.933
Hden_3150
KEGG: eli:ELI_00525 putative phosphoenolpyruvate carboxylase; Belongs to the PEPCase type 1 family.
     
 0.933
Hden_0894
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.916
Hden_1832
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: oca:OCAR_7167 L-lactate dehydrogenase.
     
 0.912
Hden_1622
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.876
Hden_2602
KEGG: pla:Plav_0292 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI).
    
 0.875
pgk
KEGG: mea:Mex_1p2369 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.871
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.870
Your Current Organism:
Hyphomicrobium denitrificans ATCC 51888
NCBI taxonomy Id: 582899
Other names: H. denitrificans ATCC 51888, Hyphomicrobium denitrificans str. ATCC 51888, Hyphomicrobium denitrificans strain ATCC 51888
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