Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
Hden_2012PFAM: MscS Mechanosensitive ion channel; KEGG: smd:Smed_1800 MscS mechanosensitive ion channel. (890 aa)    
Predicted Functional Partners:
Hden_2013
KEGG: mno:Mnod_3714 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.576
Hden_2014
KEGG: mrd:Mrad2831_5403 molybdopterin converting factor, subunit 1; TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein.
       0.576
Hden_2015
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: dar:Daro_2729 molybdopterin synthase subunit MoaE.
       0.576
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.520
Hden_0291
KEGG: mes:Meso_1752 hypothetical protein.
  
     0.513
Hden_2368
PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: tkm:TK90_2079 multiple antibiotic resistance (MarC)-related protein.
 
    0.513
Hden_0008
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; KEGG: mno:Mnod_5461 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.491
Hden_1621
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; KEGG: scl:sce5468 glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.491
Hden_1365
GAF sensor hybrid histidine kinase; KEGG: bja:bll2599 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; GAF domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver.
     
 0.474
Hden_0059
PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ccs:CCNA_01734 MarC family integral membrane protein.
  
    0.448
Your Current Organism:
Hyphomicrobium denitrificans ATCC 51888
NCBI taxonomy Id: 582899
Other names: H. denitrificans ATCC 51888, Hyphomicrobium denitrificans str. ATCC 51888, Hyphomicrobium denitrificans strain ATCC 51888
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