node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmol_0571 | Mmol_1049 | Mmol_0571 | Mmol_1049 | KEGG: mfa:Mfla_2181 hypothetical protein. | Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s); KEGG: tcx:Tcr_1150 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; CHASE domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein. | 0.646 |
Mmol_0571 | bioB | Mmol_0571 | Mmol_0572 | KEGG: mfa:Mfla_2181 hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.602 |
Mmol_0571 | bioC | Mmol_0571 | Mmol_0575 | KEGG: mfa:Mfla_2181 hypothetical protein. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.532 |
Mmol_0571 | bioF | Mmol_0571 | Mmol_0573 | KEGG: mfa:Mfla_2181 hypothetical protein. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.588 |
Mmol_0571 | bioH | Mmol_0571 | Mmol_0574 | KEGG: mfa:Mfla_2181 hypothetical protein. | bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.588 |
Mmol_0571 | trmL | Mmol_0571 | Mmol_0570 | KEGG: mfa:Mfla_2181 hypothetical protein. | RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.590 |
Mmol_1049 | Mmol_0571 | Mmol_1049 | Mmol_0571 | Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s); KEGG: tcx:Tcr_1150 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; CHASE domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein. | KEGG: mfa:Mfla_2181 hypothetical protein. | 0.646 |
Mmol_1049 | trmL | Mmol_1049 | Mmol_0570 | Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s); KEGG: tcx:Tcr_1150 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; CHASE domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein. | RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.431 |
Mmol_1984 | trmL | Mmol_1984 | Mmol_0570 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.432 |
bioB | Mmol_0571 | Mmol_0572 | Mmol_0571 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | KEGG: mfa:Mfla_2181 hypothetical protein. | 0.602 |
bioB | bioC | Mmol_0572 | Mmol_0575 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.836 |
bioB | bioF | Mmol_0572 | Mmol_0573 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.980 |
bioB | bioH | Mmol_0572 | Mmol_0574 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.819 |
bioB | trmL | Mmol_0572 | Mmol_0570 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.465 |
bioC | Mmol_0571 | Mmol_0575 | Mmol_0571 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | KEGG: mfa:Mfla_2181 hypothetical protein. | 0.532 |
bioC | bioB | Mmol_0575 | Mmol_0572 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.836 |
bioC | bioF | Mmol_0575 | Mmol_0573 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.814 |
bioC | bioH | Mmol_0575 | Mmol_0574 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.867 |
bioC | trmL | Mmol_0575 | Mmol_0570 | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.426 |
bioF | Mmol_0571 | Mmol_0573 | Mmol_0571 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | KEGG: mfa:Mfla_2181 hypothetical protein. | 0.588 |