Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mmol_1925KEGG: met:M446_3902 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein. (548 aa)    
Predicted Functional Partners:
Mmol_1924
KEGG: dac:Daci_2475 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; 5TM Receptors of the LytS-YhcK type transmembrane region; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.858
Mmol_0128
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; KEGG: pca:Pcar_2558 signal transduction protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver.
 
 
0.798
Mmol_0129
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: gsu:GSU2016 sensory box/GGDEF family protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver.
 
 
0.782
Mmol_1049
Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s); KEGG: tcx:Tcr_1150 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; CHASE domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
0.781
Mmol_1359
Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; GGDEF domain containing protein; KEGG: dar:Daro_3754 diguanylate cyclase/phosphodiesterase.
  
   0.779
Mmol_0123
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: aav:Aave_1152 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
0.771
Mmol_0432
7TM domain sensor diguanylate cyclase; KEGG: vvy:VV2671 GGDEF family protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor transmembrane region; SMART: GGDEF domain containing protein.
  
   0.771
Mmol_0644
PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; KEGG: sdn:Sden_3723 response regulator receiver.
 
 0.757
Mmol_0205
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: mfa:Mfla_0612 diguanylate phosphodiesterase.
  
   0.752
Mmol_1064
KEGG: mfa:Mfla_1388 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
 0.711
Your Current Organism:
Methylotenera mobilis JLW8
NCBI taxonomy Id: 583345
Other names: M. mobilis JLW8, Methylotenera mobilis str. JLW8, Methylotenera mobilis strain JLW8
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