Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hprKHPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (313 aa)    
Predicted Functional Partners:
Mmol_2159
Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: mfa:Mfla_0147 HPrNtr.
 
 
 
 0.936
Mmol_2158
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.915
Mmol_2160
PFAM: PTS system fructose subfamily IIA component; KEGG: mfa:Mfla_0146 PTS system fructose subfamily IIA component.
 
   
 0.772
Mmol_2163
TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: mfa:Mfla_0143 SSU ribosomal protein S30P / sigma 54 modulation protein.
     
 0.749
Mmol_2161
Conserved hypothetical protein; Displays ATPase and GTPase activities.
     
 0.707
Mmol_2164
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.580
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
  
 0.573
Mmol_2165
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mfa:Mfla_0141 ABC transporter related.
     
 0.557
Mmol_2167
PFAM: protein of unknown function DUF1239; KEGG: mfa:Mfla_0139 hypothetical protein.
 
   
 0.527
lptA
Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
     
 0.504
Your Current Organism:
Methylotenera mobilis JLW8
NCBI taxonomy Id: 583345
Other names: M. mobilis JLW8, Methylotenera mobilis str. JLW8, Methylotenera mobilis strain JLW8
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