Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mmol_2192KEGG: tgr:Tgr7_1532 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (414 aa)    
Predicted Functional Partners:
Mmol_0123
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: aav:Aave_1152 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
 
  
 0.531
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
       0.471
Mmol_1923
Diguanylate cyclase with PAS/PAC and GAF sensors; KEGG: cps:CPS_3258 sensory box protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein.
 
 
 0.468
Mmol_2309
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: dar:Daro_0217 glutamate synthase (NADH) large subunit.
     
 0.427
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.425
Your Current Organism:
Methylotenera mobilis JLW8
NCBI taxonomy Id: 583345
Other names: M. mobilis JLW8, Methylotenera mobilis str. JLW8, Methylotenera mobilis strain JLW8
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