STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caka_1152KEGG: ank:AnaeK_0230 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding. (1188 aa)    
Predicted Functional Partners:
Caka_2841
KEGG: afw:Anae109_0236 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding.
 
0.999
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.989
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.974
Caka_0509
Coagulation factor 5/8 type domain protein; KEGG: dfe:Dfer_2605 putative pyridine nucleotide- disulphide oxidoreductase; PFAM: coagulation factor 5/8 type domain protein; glucose-inhibited division protein A; SMART: LamG domain protein jellyroll fold domain protein.
  
 
 0.973
Caka_1739
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; KEGG: hoh:Hoch_5880 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
  
 
 0.973
Caka_1429
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 0.971
Caka_0479
Coagulation factor 5/8 type domain protein; KEGG: dfe:Dfer_2605 putative pyridine nucleotide- disulphide oxidoreductase; PFAM: coagulation factor 5/8 type domain protein; glucose-inhibited division protein A; Laminin G sub domain 2; SMART: LamG domain protein jellyroll fold domain protein.
  
 
 0.970
Caka_0499
Coagulation factor 5/8 type domain protein; KEGG: dfe:Dfer_2605 putative pyridine nucleotide- disulphide oxidoreductase; PFAM: coagulation factor 5/8 type domain protein; glucose-inhibited division protein A; SMART: LamG domain protein jellyroll fold domain protein.
  
 
 0.970
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.963
Caka_1049
PFAM: phosphate acetyl/butaryl transferase; KEGG: cbt:CLH_1185 phosphotransacetylase.
  
 0.962
Your Current Organism:
Coraliomargarita akajimensis
NCBI taxonomy Id: 583355
Other names: C. akajimensis DSM 45221, Coraliomargarita akajimensis DSM 45221, Coraliomargarita akajimensis str. DSM 45221, Coraliomargarita akajimensis strain DSM 45221
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