STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caka_1154Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (378 aa)    
Predicted Functional Partners:
ddl
D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.968
Caka_3067
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
   
 0.949
Caka_1153
PFAM: peptidase M22 glycoprotease; KEGG: ote:Oter_2738 hypothetical protein.
     
 0.797
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
   
 0.712
Caka_3069
TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; KEGG: ote:Oter_2633 UDP-N-acetylmuramoylalanine--D- glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein.
 
 
 
 0.699
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
   
 0.684
Caka_1155
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; KEGG: tdn:Suden_0219 multi-sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver.
  
 
 0.639
Caka_1626
PFAM: protein of unknown function UPF0079; KEGG: ote:Oter_2508 hypothetical protein.
 
  
 0.622
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.593
Caka_1152
KEGG: ank:AnaeK_0230 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding.
  
    0.538
Your Current Organism:
Coraliomargarita akajimensis
NCBI taxonomy Id: 583355
Other names: C. akajimensis DSM 45221, Coraliomargarita akajimensis DSM 45221, Coraliomargarita akajimensis str. DSM 45221, Coraliomargarita akajimensis strain DSM 45221
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