STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (515 aa)    
Predicted Functional Partners:
Caka_1876
IMP dehydrogenase; KEGG: ote:Oter_2805 malate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein.
 
 
 0.994
Caka_2311
KEGG: amu:Amuc_1941 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.988
purH
SMART: AICARFT/IMPCHase bienzyme formylation region; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: ote:Oter_3182 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein.
  
 0.973
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.953
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: ote:Oter_2512 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.941
Caka_1613
TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ote:Oter_3617 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.939
argG
TIGRFAM: argininosuccinate synthase; KEGG: ote:Oter_0688 argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.927
Caka_2234
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.913
Caka_2409
KEGG: ote:Oter_2412 stationary-phase survival protein SurE; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE.
    
 0.913
Caka_2525
PFAM: aminotransferase class I and II; KEGG: ote:Oter_3740 aminotransferase class I and II.
  
 0.909
Your Current Organism:
Coraliomargarita akajimensis
NCBI taxonomy Id: 583355
Other names: C. akajimensis DSM 45221, Coraliomargarita akajimensis DSM 45221, Coraliomargarita akajimensis str. DSM 45221, Coraliomargarita akajimensis strain DSM 45221
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